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Showing profile for Prof. Zhen Liu Ph. D

Position: Professor
Institution: Nanjing University
Department: School of Chemistry and Chemical Engineering
Address:  163 Xianlin Ave.
 Nanjing, Jiangsu
 CN, 210023

Email: Not public

Personal statement:

Dr. Zhen Liu obtained his Ph.D. from Dalian Institute of Chemical Physics, Chinese Academy of Sciences in 1998. He was appointed as a full professor at Nanjing University Dec. 2005. He was awarded the title í░New Century Excellent Talents in Universitiesí▒ by the Ministry of Education of China in 2008. He was selected as í░Excellent Young Leading Facultyí▒ by Nanjing University in 2009. He was appointed as an adjunct professor at the Faculty of Engineering, University of Waterloo from 2011 to 2014. He was awarded the Science & Technology Award (First Class) by China Association for Instrumental Analysis (CAIA) in 2011. In 2014, he was awarded the National Science Fund for Distinguished Young Scholars. His main research is focused on the development of innovative principles, functional materials and approaches for biorecognition, bioseparation and biodetection, based on molecular imprinting, liquid chromatography, capillary electrophoresis, biomass spectrometry, Raman spectrometry and so on. He has authored or coauthored 1 monograph, 5 book chapters and 110+ peer-reviewed journal papers, which have already obtained 2700+ citations (Google Scholar). His h-index is 32 (Google Scholar). In the field of molecular imprinting, he has established several facile and widely applicable molecular imprinting approaches, such as 1) photolithographic boronate affinity molecular imprinting, 2) boronate affinity-based controllable oriented surface imprinting, and 3) Dual-template docking oriented molecular imprinting. MIPs produced by these approaches exhibited several highly desirable properties, with which promising applications in disease diagnosis, proteomic analysis and bioimaging have been demonstrated.


Previous posts:

Dates: 2002-2005Institution: University of Waterloo
Job title: Post-doctoral fellow

Dates: 2000-2002Institution: Himeji Institute of Technology
Job title: Post-doctoral fellow

Dates: 1998-2000Institution: Dalian Institute of Chemical Physics
Job title: Research associate

Selected Publications:
1: Li L et al., Photolithographic Boronate Affinity Molecular Imprinting: A General and Facile Approach for Glycoprotein Imprinting.
Angewandte Chemie International Edition, 52, (29), 7451-7454, (2013)

2: Bi XD et al., Enzyme Activity Assay of Glycoprotein Enzymes Based on a Boronate Affinity Molecularly Imprinted 96-Well Microplate.
Analytical Chemistry, 86, (24), 12382-12389, (2014)

3: Bi XD et al., Facile Preparation of Glycoprotein-Imprinted 96-Well Microplates for Enzyme-Linked Immunosorbent Assay by Boronate Affinity-Based Oriented Surface Imprinting.
Analytical Chemistry, 86, (1), 959-966, (2014)

4: Wang SS et al., Affinity-tunable specific recognition of glycoproteins via boronate affinity-based controllable oriented surface imprinting.
Chemical Science, 5, (3), 1135-1140, (2014)

5: Ye J et al., A Boronate Affinity Sandwich Assay: An Appealing Alternative to Immunoassays for the Determination of Glycoproteins.
Angewandte Chemie International Edition, 53, (39), 10386-10389, (2014)

6: Bie ZJ et al., Boronate-Affinity Glycan-Oriented Surface Imprinting: A New Strategy to Mimic Lectins for the Recognition of an Intact Glycoprotein and Its Characteristic Fragments.
Angewandte Chemie International Edition, 54, (35), 10211-10215, (2015)

7: Chen Y et al., Dual-template docking oriented molecular imprinting: a facile strategy for highly efficient imprinting within mesoporous materials.
Chemical Communications, 51, (54), 10929-10932, (2015)

8: Yin DY et al., Surface-enhanced Raman scattering imaging of cancer cells and tissues via sialic acid-imprinted nanotags.
Chemical Communications, 51, (100), 17696-17699, (2015)

9: Li DJ et al., Boronate affinity materials for separation and molecular recognition: structure, properties and applications.
Chemical Society Reviews, 44, (22), 8097-8123, (2015)

10: Chen Y et al., Coupling of Phosphate-Imprinted Mesoporous Silica Nanoparticles-Based Selective Enrichment with Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry for Highly Efficient Analysis of Protein Phosphorylation.
Analytical Chemistry, 88, (2), 1447-1454, (2016)


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