The Society for Molecular Imprinting 
Event, Conference or Meeting (this event occurred in the past)
Master SPR for life sciences – from affinity and kinetic constants to conformation changes, hands-on training on a pre-selected set of molecules, SPR experiment planning, assay development, understanding of the underlying physico-chemical phenomena to resolve challenges, new applications of SPR from science and industry. You will become an independent expert in SPR.
AUDIENCE: MSc and PhD students as well as industrial participants
PRE-REQUISITES: Basic laboratory skills, background in pharmaceutics, chemistry, physical chemistry or biomaterials.
WHAT WILL YOU LEARN: Master SPR for life sciences – from affinity and kinetic constants to conformation changes, hands-on training on a pre-selected set of molecules, SPR experiment planning, assay development, understanding of the underlying physico-chemical phenomena to resolve challenges, new applications of SPR from science and industry. You will become an independent expert in SPR.
LECTURERS:
Prof. Richard O’Kennedy (Dublin City University/Biotechnology), Prof. Vesa Hytönen (University of Tampere/Protein Dynamics), Dr. Tapani Viitala (University of Helsinki/Biopharmaceuticals), Dr. Arnoud Marquart (Sanquin Blood Supply Foundation, Founder of sprpages.nl), Prof. Jouko Peltonen (Åbo akademi/Physical chemistry), Prof. Peter Mattjus (Åbo akademi/Biochemistry), As.prof. Karl Andersson (Uppsala university/Immunology, Ridgeview Instruments)
HANDS-ON TRAINING
- Antibody-antigen interactions
- And one of the following tracks based on your interests:
- small drug molecules,
- interaction of drugs with lipids,
- interaction of drugs with living cells,
- interaction on biomaterial interfaces, or
- biomolecular quantification
From experiment planning, sensor surface selection, buffers, regeneration, through assay development, sample preparation and characterization to SPR measurements, data analysis and validation.
SUPPORTING LECTURES
- SPR history and theory introduced by one of the fathers of the technology
- SPR instrument configurations
- Sensor surfaces and immobilization strategies
- Measurement disturbances and artefacts (how does it show in measurements, theoretical reasoning for the effect, strategies to mitigate the effect)
- From sensogram to affinity and kinetic constants
- From measurement to conformation change
- Validation of results (ITC, AFM, TOF-SIMS,..)
- Application highlights from research and industry
| Posted on 17 March 2017 at 14:01:51 by Willem Marinus Albers |  |
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