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Postdoc opportunity in Rational MIP Design at UTC, Compiegne (France)
Starting date for applications: 01 Apr 2017
Closing date for applications: 20 May 2017
Location: University of Technology, GEC FRE 3580, Compiegne, FRANCE
Description of job:University and locationThe University of Technology of Compiegne (UTC) is recruiting a postdoctoral research associate to take a leading role in the project BESTMIP entitled “Generic and rational design of molecularly imprinted polymers”. The successful candidate will be under the direct supervision of Luminita Duma and will join the research group of Karsten Haupt “Biomimetism and Functional Material” in the Laboratory of Enzyme and Cell Engineering.UTC has the particular advantage of being both a university and an engineering school with innovative training and pedagogical programs and interdisciplinary research programs developed by its nine research units. Compiegne is a nice and pleasant city to live in, located at the confluence of Aisne and Oise rivers and at less than one hour by train or car from Paris. Charles de Gaulle airport is nearby and permits straightforward international travels.RoleThe aim of this project is to design a rational approach for the synthesis of molecularly imprinted polymers (MIP) for target molecules which are disease biomarkers. The interaction between functional monomers and the target will be characterized both in silico and experimentally in order to select, for the synthesis of MIPs, the functional monomers and the solvent leading to the strongest complex. Hence, it is expected that the final MIP will show strong affinity and selectivity for its ligand. Various techniques will be used to study the complexation of the target by functional monomers and the polymer-ligand binding mechanism: molecular modelling, nuclear magnetic resonance, isothermal calorimetry and surface plasmon resonance. The polymers will be obtained by free-radical polymerizations and solid phase synthesis. Ideal CandidateDegrees: The candidate should have a PhD degree in chemistry or physical-chemistry.Theoretical and practical skills: The ideal candidate should have know-how in free-radical polymerizations and solid-phase synthesis of MIPs for the molecular recognition of peptides and proteins. Experience on molecular modelling in molecular imprinting can be a plus, but not mandatory. We seek a very motivated candidate who should demonstrate initiative, creativity, and effective work team skills. Scientific discipline, integrity, and reliability are essential.What to do?Motivated candidates should send a detailed CV and a cover letter, as well as any questions, to luminita.duma@utc.fr
Posted on 1 April 2017 at 10:34:16 by Mike Whitcombe |  |
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The Society for Molecular Imprinting
